Will Little @wclittle Subscribe

Managing Director at Prota Ventures.
I'm a bioengineer-turned-software-developer and venture builder/investor. Learn more about me professionally on LinkedIn, personally here, and check out the podcast I host, Ventures.

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 Will Little

Sep 8, 2020
Health Science Startups Ventures Podcast

COVID-19 response and innovation at University of Washington Medicine. Plus, a call-to-action for medical technology entrepreneurs :: with Danica Little, Dimitry Levin, and Dr. Robert Sweet

In this episode of Ventures we look at the response to COVID-19 by teams involved with emergency preparedness and innovation at University of Washington (UW) Medicine in Seattle. We also discuss the need and options available for startups to collaborate with UW Medicine to help - not only with COVID-19 relief - but with general medtech and telehealth innovation to provide better care for patients in a post-COVID-19 world.

Will Little

Sep 1, 2020
Health Science Will's General Newsletter Social Entrepreneurship

Social entrepreneurship, Nuralink, Reddit, and my health science N=1 experiment this past spring

This week’s episode of Ventures explores entrepreneurial efforts to help the poorest of the poor globally. There is a lot to learn and digest here, and I’m excited to share this important conversation. (Also, a few thoughts on Nuralink, my Reddit post from last week, and my final writeup of the Whoop/AppleWatch/OuraRing N=1 experiment).
Will Little

Sep 1, 2020
Health Science N=1 Experiments

Whoop vs. Oura Ring vs. Apple Watch for Optimizing Sleep and Workout Performance with Continuous Glucose Monitoring and One Meal a Day: Part 2

In the initial post for this series I shared the basic experimental setup and example data output. Here, in the second and final part of this series, I’m going to dive into notable variables and examine the overall data to conclude initial lessons learned from this 30-day experiment. As a quick reminder, during the initial part of the spring 2020 COVID-19 quarantine I decided to wear a Continuous Glucose Monitor while testing the differences between Whoop, Apple Watch, and Oura Ring. I had already been doing daily time-window eating between ~5:30-7:30pm (i.e. One Meal a Day, “OMAD”) for 6-7 months, and my ultimate goal with this N=1 experiment was to figure out how to optimize sleep and workout performance by tweaking food/drink intake and timing.

Will Little

Sep 1, 2020
Ventures Podcast Social Entrepreneurship

Global impact investing, social entrepreneurship, and Global Brigades :: with Steve Atamian and Brian Howe

In this episode of Ventures we explore the world of impact investing & social entrepreneurship to help the poorest of the poor around the globe. We hear and discuss the founding story of Global Brigades, the world’s largest student-led movement for global health (approximately one in five medical students today have gone on a Brigade). We also hear the launch announcement of Eskala, a for-profit company with an ambitious (and believable) 20-year plan to help end poverty for 18 million people.
Will Little

Aug 29, 2020
Software Development Ruby on Rails

How to setup Windows to begin developing Ruby on Rails Web Applications

Getting your local computer setup for developing web applications is one of the most difficult aspects of learning. In this tutorial, we will go all the way from a generic Windows 10 install to having a running Ruby on Rails application that you can see in a web browser on your machine.

Will Little

Aug 29, 2020
Software Development Ruby on Rails

How to setup a Mac to begin developing Ruby on Rails Web Applications

Getting your local computer setup for developing web applications is one of the most difficult aspects of learning. In this tutorial, we will go all the way from a generic MacOS install to having a running Ruby on Rails application that you can see in a web browser on your machine.

Will Little

Aug 25, 2020
Will's General Newsletter

Finding a technical co-founder, starting a golf gear company, turning 40, and a Reddit post I wrote this morning reflecting on the past 20 years

I’m excited to share this week’s podcast conversation with the amazing Gabe Coyne (designer, developer, technologist, and entrepreneur) and his new startup, Stix. Also, while I haven’t been super active on Reddit the past decade, I wrote up a post in /r/Entrepreneur a couple hours ago and also popped it up on my Satchel site here.
Will Little

Aug 25, 2020
Startups Financial Modeling About Will

I turned 40 this summer. I spent my 20s building businesses and my 30s investing in early stage founders. Here are a few things I’ve learned thus far.

Greetings to anyone else out there in the Oregon Trail Generation that is crossing (or has recently crossed) the 40 mark. :) We’re old enough to remember an analog world, but young enough to have grown up with the early days of the Internet. It’s been quite a ride thus far.

Will Little

Aug 25, 2020
Startups Ventures Podcast

Finding a technical co-founder, becoming an angel developer, and starting a new golf gear company :: with Gabe Coyne

One of the most common questions in the startup space is how to find a technical co-founder to design and build your product. In this episode of Ventures, we discuss in depth both how to become a great startup CTO and to find one in your network. We also talk about the founding story of Stix (https://stix.golf/), a new golf brand focused on middle-market, stylish clubs for the casual golfer.

Will Little

Aug 18, 2020
COVID-19 Startups Will's General Newsletter

New podcast episode on the founding story of Kickstarter & empowering creatives :: Plus, how to think like a (good) epidemiologist

It was fascinating to hear the founding story of Kickstarter and discuss with Charles and Wilson how to best support founders in this COVID-19 era, especially those inventing, creating, and selling tangible goods. Also, let's talk about Bayesian inference machines.

Will Little

Aug 18, 2020
Startups Ventures Podcast

Co-founding Kickstarter, empowering creatives, and starting a tangible goods company in a pandemic :: with Charles Adler and Wilson Fong

In this episode of Ventures we look at the founding story of Kickstarter and discuss how to support and advise founders that are bringing new companies to life. We discuss specifically the challenges facing founders selling tangible goods in the COVID-19 era and how online resources and communities can be leveraged to optimize success in this difficult market landscape.

Will Little

Aug 11, 2020
Blockchains Visual Design Will's General Newsletter Branding Web3

New podcast on startup branding strategies, plus a new screencast on crypto trading with the Ichimoku Cloud indicator system

I recorded a podcast episode with brand strategist Elisabeth Hass and visual designer Natalie Grummer on all-things startup branding, competitive analysis, naming, logo design. Also, in Q4 2017 I was introduced to a simple indicator system that has proven helpful through bear, horizontal, and bull markets, and I recorded a screencast this morning to share with you all.
Will Little

Aug 11, 2020
Blockchains Crypto Trading Web3

Crypto Trading with the Ichimoku Cloud Indicator System

In this video I walk through how I use the Ichimoku system - both algorithmically and manually - for trading bitcoin and other cryptocurrencies on a day-to-day and week-to-week basis. The Ichimoku system is a quick way to assess the current trend of a market and assign probabilities to future movement to inform potential long and short positions.
Will Little

Aug 11, 2020
Startups Visual Design Ventures Podcast Branding

Startup Branding :: Strategy, Competitive Positioning, Personas, Naming, and Visual Design :: with Elisabeth Hass and Natalie Grummer

Most founders don’t pay enough attention to foundational branding processes, which often results in customer confusion, off-putting names/visuals, and/or an untimely death for new startups. In this episode, we dive into many aspects of branding a startup, from naming and competitive positioning to visual design and personas/values, including specific recommendations for designing a logo, mockups, and prototypes.

Will Little

Aug 5, 2020
Blockchains Sleep About Will Will's General Newsletter

Home education this fall and beyond, measuring sleep, and Ethereum turns five

I’m excited to release the fourth episode of the Ventures podcast today with my wife Sarah and our friend Abby as guests, check it out. And while many in the crypto community have mixed feelings about the state of the industry, and/or think it’s straight-up boring currently, there are many aspects of the ETH1 to ETH2 transition in particular that are worth learning.