Will Little @wclittle Subscribe

Managing Director at Prota Ventures.
I'm a bioengineer-turned-software-developer and venture builder/investor. Learn more about me professionally on LinkedIn, personally here, and check out the podcast I host, Ventures.

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Topic:   About Will
 Will Little

Aug 10, 2021
Blockchains Software Development About Will Ventures Podcast Web3

Web 2.0 vs. Web 3.0 development, design, and data architecture concerns :: with Andrew Cronk

In this episode of Ventures, I start with a quick summer 2021 reflection and then dive into a short clip from Episode 48 with Andrew Cronk (https://www.linkedin.com/in/andrewcronk/). Web 3.0 entrepreneurs and decentralization application (dApp) developers will need to approach software engineering concerns such as user identity and data storage/querying in different ways than the Web 2.0 era. Andrew’s initial insights into this transition are enormously helpful.

Will Little

May 18, 2021
Startups Sociology About Will Ventures Podcast

Self-discovery, discerning our limits, and transitioning from idealism :: with Kathryn Little

In this special episode of Ventures, Kathryn Little (my amazing mother) and I discuss finding oneself, discovering purpose, transitioning out of idealism, saying yes and no to the right things, processing grief, marriage, parenting, and being who you are as an entrepreneur and human being. Indeed, when thinking about the best possible guest for this episode, I asked my mother and she graciously agreed to share her story and insights.
Will Little

Apr 20, 2021
Sociology About Will

If it's going to trigger them, don't send it

I turned 40 last summer and, while apparently 40 is the new 30, I still feel “old”, especially with two teenagers in the house now. I’ve been reflecting on the classic question: “What advice would I give my younger self?” There is an immediate topic that comes to mind: written communication.
Will Little

Aug 25, 2020
Startups Financial Modeling About Will

I turned 40 this summer. I spent my 20s building businesses and my 30s investing in early stage founders. Here are a few things I’ve learned thus far.

Greetings to anyone else out there in the Oregon Trail Generation that is crossing (or has recently crossed) the 40 mark. :) We’re old enough to remember an analog world, but young enough to have grown up with the early days of the Internet. It’s been quite a ride thus far.

Will Little

Aug 5, 2020
Blockchains Sleep About Will Will's General Newsletter

Home education this fall and beyond, measuring sleep, and Ethereum turns five

I’m excited to release the fourth episode of the Ventures podcast today with my wife Sarah and our friend Abby as guests, check it out. And while many in the crypto community have mixed feelings about the state of the industry, and/or think it’s straight-up boring currently, there are many aspects of the ETH1 to ETH2 transition in particular that are worth learning.
Will Little

Jul 19, 2020
Health Science Sleep About Will N=1 Experiments

Whoop vs. Oura Ring vs. Apple Watch for Optimizing Sleep and Workout Performance with Continuous Glucose Monitoring and One Meal a Day: Part 1

Wearables are all the rage these days. However, beyond their fancy and comprehensive marketing campaigns, I’m curious - from a scientific perspective - how helpful, reliable, and accurate are these products? I’m skeptical, of course, but the future looks promising. While these current products are far from perfect, they hint at an exciting vision for improving our health.
Will Little

Jun 20, 2020
About Will

Personal bio: How I think about science, family, health, hobbies, etc...

You can read highlights about my professional career over on LinkedIn, but this page - for those curious - explains who I am personally and how I think about the world. While I write mostly about startups, blockchains, health science, and software development, occasionally topics come up that require diving into non-technical disciplines. Here, I’ll explain some background about how I approach those topics.

Will Little

Jun 20, 2020
Satchel About Will Will's General Newsletter

Summer Update: A new newsletter on a new platform. Welcome!

For those new to this newsletter, welcome! Feel free to connect with me on LinkedIn or learn more about me at my new bio page. I’ve decided to merge a few lists from over the years into this general newsletter, so feel free to duck out at any time via the unsubscribe link in your email. Or - if you’d like to follow specific topics as I post them - check out my new subscribe page on Satchel, a new publishing platform that I’m excited to introduce today.

Will Little

May 14, 2018
Blockchains Proof-of-Stake About Will Web3

A primer on Proof-of-Stake and why it matters for the future of blockchains

There is a major, multi-faceted shift happening right now in the world of crypto. It’s difficult to see given how noisy, complex, disjointed, and interdisciplinary the information flow and topics are in the community; but new consensus protocols combined with a maturing regulatory landscape are setting the stage to unify four groups that are often in conflict within a blockchain project...