Will Little @wclittle Subscribe

Managing Director at Prota Ventures.
I'm a bioengineer-turned-software-developer and venture builder/investor. Learn more about me professionally on LinkedIn, personally here, and check out the podcast I host, Ventures.

Featured Topics

Other Topics

+ Show
Topic:   Keto
 Will Little

Sep 29, 2020
Health Science Startups Keto Will's General Newsletter

From idea to exit in a few years, setting up a mac for web development, and followup from last week's episode on Lipidology

This week I’m honored to have two friends of mine share their story of building and growing a company, getting acquired, and merging in with a larger organization. I also share a screencast for Mac users setting up their computers for web development, and follow up from last's week's episode on lipidology.
Will Little

Sep 22, 2020
Health Science Keto Software Development Ruby on Rails Will's General Newsletter

Lipidology with Dave :: Code with Isaac. Plus, are "mainstream" and "keto" actually getting along?

In this week’s episode of Ventures, Dave Feldman (@DaveKeto) was kind enough to sit down with me and answer a ton of questions. Also, Isaac from South Carolina (14yrs old) sat down with me to walk through setting up his local Windows machine for Ruby on Rails web development.

Will Little

Sep 22, 2020
Health Science Keto Ventures Podcast

Cholesterol, lipidology, ketogenic diets, N=1 experiments, and the future of health technology :: with Dave Feldman

In this episode of Ventures, my guest Dave Feldman (@DaveKeto) and I discuss a variety of topics related to lipids, immunology, ketogenic diets, and the future of health tech. I first came across Dave’s work when I noticed my cholesterol levels (specifically LDL-C) raised significantly when fasting and/or low-carb dieting, and I found that there is a large community of people who have noticed the same phenomenon. Dave has helped pioneer efforts to formulate hypotheses around why this might be the case, and why LDL levels in our blood may be considerably more complex than we’ve been led to believe.

Will Little

Dec 14, 2017
Health Science Keto

The Science of Healthy Fats

The world is waking up to the reality that sugar and refined carbohydrates are more to blame for the diseases of western civilization than salt or fats. Still, there remains confusion about the health implications of consuming fat. What does modern research have to say about the effects of saturated fat, omega-3s/6s/9s, and short/medium/long-chain triglycerides? What are nutritionists referring to when they use the term “healthy fats”, and what exactly makes fat healthy versus unhealthy?
Will Little

Oct 28, 2017
Health Science Keto

The science of salt and electrolytes (are we consuming enough?)

Modern science has revealed that we were wrong (and fooled) yet again. As it turns out, mineral deficiencies are likely more of a problem than we realize, as not consuming enough salt and electrolytes is both easy to do and dangerous for our health.
Will Little

Oct 18, 2016
Health Science Keto

The 43+ health benefits of ketogenic dieting (in addition to weight loss)

For those unfamiliar, ketogenic dieting is any diet plan “low-carb” enough to switch your body into a state of producing and burning a significant amount of ketones, specifically acetoacetate (AcAc) and its derivatives beta-hydroxybutyrate (BHB) and acetone. These molecules, especially AcAc and BHB, are used by the brain and other tissues for energy, and facilitate a number of health benefits that I’ll address below.
Will Little

Jan 18, 2016
Health Science Keto

Summarizing the science behind ketogenic (low-carb) diets

After publishing The Science Behind Fat Metabolism a couple weeks ago, I received a tremendous amount of helpful feedback from scientists, medical professionals, and other health experts. Cheers, Internet. I appreciate the feedback and refinement. I’ve updated the article accordingly and will continue to do so as more comments are submitted. I also got a bunch of questions about low-carb dieting, hence my attempt in this article to summarize the underlying science. As always, if you read anything below that needs changing, let me know and I’ll do so quickly.