Will Little @wclittle Subscribe

Managing Director at Prota Ventures.
I'm a bioengineer-turned-software-developer and venture builder/investor. Learn more about me professionally on LinkedIn, personally here, and check out the podcast I host, Ventures.

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Topic:   Health Science
 Will Little

Oct 28, 2017
Health Science Keto

The science of salt and electrolytes (are we consuming enough?)

Modern science has revealed that we were wrong (and fooled) yet again. As it turns out, mineral deficiencies are likely more of a problem than we realize, as not consuming enough salt and electrolytes is both easy to do and dangerous for our health.
Will Little

Mar 21, 2017
Health Science Sleep

The Science of Optimal Sleep: Introduction to Nutritional Biochemistry, Part 5

In the previous four articles in this series we looked at fat loss, muscle gain, hydration, and flexibility. Here, we finish the series by turning our attention to sleep.
Will Little

Feb 27, 2017
Health Science

How to increase muscle flexibility: Introduction to Nutritional Biochemistry, Part 4

In the first three articles in this series we looked at fat loss, muscle gain, and hydration. Here, we turn our attention to the science behind muscle flexibility.
Will Little

Feb 4, 2017
Health Science

How to stay hydrated (and reduce headaches, hangovers, and fat): Introduction to Nutritional Biochemistry, Part 3

In the first two articles of this series we looked at the science behind how to shrink fat cells and grow muscle cells. Here, we take aim at hydration.
Will Little

Jan 13, 2017
Health Science Strength Training

How to grow muscles: Introduction to Nutritional Biochemistry, Part 2

After looking at the science behind how to shrink fat cells in the previous post of this 5-part series, we now turn our attention to muscles and how to increase their size.
Will Little

Dec 19, 2016
Health Science

The calories vs. hormones debate for shrinking fat cells: It’s both…and it varies from person to person, season to season

So there are pro-macro and anti-macro tribes out there, each with valid arguments. (If you’re not up on the lingo, when a fitness-y person asks “what are your macros?”, they are asking what your daily calories are from carb/protein/fat).
Will Little

Dec 10, 2016
Health Science

How to shrink fat cells: Practical Nutritional Biochemistry, Part 1

We’re going to laser-beam in this 5-part series on the basic science behind how to shrink fat cells, grow muscle cells, get flexible, stay hydrated, and sleep well. We’ll move quickly and link to a variety of sources for further reading.
Will Little

Oct 18, 2016
Health Science Keto

The 43+ health benefits of ketogenic dieting (in addition to weight loss)

For those unfamiliar, ketogenic dieting is any diet plan “low-carb” enough to switch your body into a state of producing and burning a significant amount of ketones, specifically acetoacetate (AcAc) and its derivatives beta-hydroxybutyrate (BHB) and acetone. These molecules, especially AcAc and BHB, are used by the brain and other tissues for energy, and facilitate a number of health benefits that I’ll address below.
Will Little

Jan 18, 2016
Health Science Keto

Summarizing the science behind ketogenic (low-carb) diets

After publishing The Science Behind Fat Metabolism a couple weeks ago, I received a tremendous amount of helpful feedback from scientists, medical professionals, and other health experts. Cheers, Internet. I appreciate the feedback and refinement. I’ve updated the article accordingly and will continue to do so as more comments are submitted. I also got a bunch of questions about low-carb dieting, hence my attempt in this article to summarize the underlying science. As always, if you read anything below that needs changing, let me know and I’ll do so quickly.
Will Little

Jan 2, 2016
Health Science

The Science Behind Fat Metabolism

The concentration of glucose in your blood is the critical upstream switch that places your body into a “fat-storing” or “fat-burning” state. The metabolic efficiency of either state — and the time it takes to get into one from the other — depends on a large variety of factors such as food and drink volume and composition, vitamin and mineral balances, stress, hydration, liver and pancreas function, insulin sensitivity, exercise, mental health, and sleep.